“Bone-like” Nanofibrous Scaffold May Spur Osseointegration in Orthopaedic Applications

Researchers are investigating the performance of electrospun polyvinyl alcohol, nano-hydroxyapatite and collagen nanofibers as biomimetic materials for modifying implant surfaces to encourage osseointegration for orthopaedic applications.

Electrospinning is a technique that may enable fabrication of nanofibrous structures that mimic an extracellular matrix, enhancing the adhesion and proliferation of interacting cells. Potential effects in enhancing implant fixation in animal models will be investigated.

This study was conducted by Dr. Weiping Ren’s group from the department of Biomedical Engineering at Wayne State University.

REFERENCES

“Bone-like” electrospun nanofibres promote osteoblast activity. Nanotechweb.org, March 20, 2102.

Electrospun polyvinyl alcohol–collagen–hydroxyapatite nanofibers: a biomimetic extracellular matrix for osteoblastic cells. Wei Song et al 2012 Nanotechnology 23 115101.